WebPhenylephrine is a synthetic noncatecholamine α1 agonist and produces dose-dependent vasoconstriction of cutaneous, muscular, mesenteric, splanchnic, and renal vasculature … WebPhenylephrine / metabolism* Protein Binding Rats Tomography, Emission-Computed Substances Adrenergic Agonists Dopamine Plasma Membrane Transport Proteins Ligands Membrane Glycoproteins Membrane Transport Proteins Nerve Tissue Proteins SLC6A3 protein, human Slc6a3 protein, rat Carbon Dioxide Phenylephrine Norepinephrine
Phenylephrine Monograph for Professionals - Drugs.com
WebJul 14, 2024 · Phenylephrine belongs to the class of medicines known as nasal decongestants. It may also be called a vasopressor or a selective alpha-1-adrenergic receptor agonist. 2. Upsides Tablets, chewable tablets, liquid and nasal preparations of phenylephrine are used to treat nasal and sinus congestion. Phenylephrine is a selective α 1-adrenergic receptor agonist which results in the constriction of both arteries and veins. Phenylephrine was patented in 1927 and came into medical use in 1938. It is available as a generic medication. Unlike pseudoephedrine, abuse of phenylephrine is very uncommon. See more Phenylephrine is a selective α1 receptor agonist medication primarily used as a nasal decongestant, to dilate the pupil, to increase blood pressure, and to relieve hemorrhoids. Phenylephrine can be taken by mouth, as a nasal … See more Decongestant Phenylephrine is used as a decongestant sold as an oral medicine or as a nasal spray. It is a common ingredient in over-the-counter decongestants in the United States. Phenylephrine is … See more • "Phenylephrine". U.S. National Library of Medicine: Drug Information Portal. See more Phenylephrine may cause side effects such as headache, reflex bradycardia, excitability, restlessness and cardiac arrhythmias. Phenylephrine is not suggested for use in … See more Pharmacodynamics Phenylephrine is a sympathomimetic drug, which means that it mimics the actions of epinephrine (commonly known as adrenaline) or … See more ravens seating chart with seat numbers
Brompheniramine Monograph for Professionals - Drugs.com
WebSep 28, 2015 · The disposition of phenylephrine is governed by extensive presystemic metabolism via sulfate conjugation, the involvement of non-cytochrome P450-mediated, … WebDrug Metabolism Letters 2004년 8월 The current study was designed to identify the major human SULT(s) responsible for the sulfation of phenylephrine. Of the twelve human SULTs analyzed, SULT1A3 displayed the strongest sulfating activity toward phenylephrine. The enzyme exhibited a pH optimum spanning 7 - 10.5. WebMetabolism to phenolic conjugates mainly after oral ingestion, and to m-hydroxymandelic acid after i.v. injection, again demonstrated that m-hydroxylated amines are … simon yee siak choon