Incidence of rhabdomyolysis with daptomycin
WebDaptomycin is associated with a number of adverse effects including eosinophilic pneumonia, hypersensitivity reaction, myopathy, rhabdomyolysis, headache and … WebSep 29, 2024 · Introduction. Daptomycin is a lipopeptide antibiotic often used for the treatment of methicillin-resistant Staphylococcus aureus (MRSA). Despite its clinical utility, there have been a few reports of rhabdomyolysis related to daptomycin use [1,2].In this report, we present a case of rhabdomyolysis, severe hyperkalemia, and acute kidney injury …
Incidence of rhabdomyolysis with daptomycin
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http://cid.oxfordjournals.org/content/42/12/e108.full#:~:text=To%20our%20knowledge%2C%20this%20is%20the%20first%20documented,0.2%25%20of%20the%20study%20population%20reported%20myopathy%20%5B2%5D. WebJan 16, 2024 · Rhabdomyolysis means dissolution of skeletal muscle, and it is characterized by leakage of muscle cell contents, myoglobin, sarcoplasmic proteins (creatine kinase, lactate dehydrogenase, aldolase, …
WebRhabdomyolysis is a known possible complication associated with daptomycin therapy. However, previous findings were predominantly in phase 1 and 2 trials, and the effects … WebJan 1, 2024 · There was no other potential source of rhabdomyolysis in this patient and this is the first case report documenting concomitant renal injury as well as DILI secondary to daptomycin administration. Another case reported in 2007 similarly found elevations in CK as well as transaminase levels with significant muscle weakness after daptomycin ...
WebEarly-onset rhabdomyolysis related to daptomycin use. Early-onset rhabdomyolysis related to daptomycin use Int J Antimicrob Agents. 2007 Nov;30(5):472-4. doi: … WebConclusion: Daptomycin can be associated with elevations in CPK level and rhabdomyolysis despite reduction of dose. A baseline CPK level before starting …
WebNov 23, 2024 · Citation 8 In contrast, a study by Graham et al Citation 9 in 2004 reported an average incidence of 0.44 in 10,000 patients (who developed rhabdomyolysis) being treated with atorvastatin, simvastatin, or pravastatin, with a 95% confidence interval of 0.20–0.84. These patients had been taking lipid-lowering agents alone or in combination.
WebJun 15, 2006 · The use of daptomycin has been associated with an elevation in creatine phosphokinase level, with a reported incidence of 2.8% in phase III clinical trials. … graphtec 9000 plotterWebApr 16, 2024 · Background: Daptomycin-associated myopathy has been identified in 2-14% of patients, and rhabdomyolysis is a known adverse effect. Although risk factors for daptomycin-associated myopathy are... chiswell \u0026 co southamptonchiswell\\u0027s inheritanceWebThe incidence of myopathy and rhabdomyolysis were highest during the first year and then decreased during the subsequent years of treatment. In another clinical outcomes study in which 10,269 adult patients were treated with simvastatin 40 mg per day (mean follow-up of 5 years), the incidence of myopathy/rhabdomyolysis was <0.1% in patients ... graphtec 60 inch plotterWebWe have encountered numerous cases of rhabdomyolysis associated with acute pesticide intoxication; however, the cause, incidence, and treatment outcomes of rhabdomyolysis … chiswell trialWebDaptomycin requires prior approval. Baseline CK followed by weekly CK should be measured in patients placed on daptomycin due to increased risk of rhabdomyolysis. Increased dose of daptomycin may be indicated with documented MRSA bacteremia. Infections due to fungi, mycobacteria, or Actinomyces require longer durations of therapy – chiswell\u0027s inheritanceWebDaptomycin has been associated with raised creatine kinase activity, with a reported incidence of 2.8% in phase III clinical trials (167 A). Rhabdomyolysis has also been described (168 A ) . A 45-year-old woman with refractory acute myeloid leukemia was given intravenous daptomycin 550 mg (6 mg/kg) every 24 hours because of bacteremia due to ... graphtec acoustic saddles