Human hsd17b13

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August undefined, 2024

WebLentiviral human HSD17B13 shRNA (UBC) (100) Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, 4x25 ul each, functional titer of 1x10^8 TU/ml. $1,980.00. Add to Cart. WebDescription: Homo sapiens hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13), transcript variant A, mRNA. (from RefSeq NM_178135) Gencode Transcript: ENST00000328546.5 Gencode Gene: ENSG00000170509.12 Transcript (Including UTRs)

HSD17B13 News opnMe Boehringer Ingelheim

WebHSD17B13 inhibitor BI-3231 Social share buttons Highlights BI-3231 is a potent inhibitor of human and mouse hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) and is highly selective for it over its phylogenetically closest isoform HSD17B11. WebJun 1, 2024 · Recent study showed that hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), an enzyme with unknown biological function, is a novel liver-specific lipid droplet (LD)-associated protein in mouse and humans. HSD17B13 expression is markedly upregulated in patients and mice with non-alcoholic fatty liver disease (NAFLD). recycling ielts speaking

Integrated Proteomics and Bioinformatics to Identify Potential ...

WebInformed consent was obtained from each patient. The study was approved by the Protection of Human Subjects Committee of Nanfang Hospital (approval no. NFEC-202401-K4). We obeyed the principles of the 1983 Declaration of Helsinki. ... which is associated with liver injury progression. 38 Lu et al found that HSD17B13 was a tumor suppressive … WebHSD17B13 (Hydroxysteroid 17 Beta Dehydrogenase 13) is a Protein Coding gene. Diseases associated with HSD17B13 include5 Alpha Reductase … WebNov 2, 2024 · HSD17B13 is a newly identified gene encoding a liver-enriched and hepatocyte-specific LD protein that enhances hepatic lipogenesis and promotes the pathogenesis of NAFLD 7. In the recent years,... recycling ifrs 9

17-Beta Hydroxysteroid Dehydrogenase 13 Deficiency …

Anti-HSD17B13 Antibodies Invitrogen - Thermo Fisher Scientific

WebHuman Hsd17b13 (17-beta-hydroxysteroid dehydrogenase 13) ELISA. Hsd17b13 (17-beta-hydroxysteroid dehydrogenase 13) is a member of the short-chain dehydrogenase/reductase family. Hsd17b13 catalyzes the reduction of steroids such as progesterone and testosterone. Hsd17b13 is known to be expressed in adrenal gland, uterus, skin and … WebThe human HSD17B13 gene encodes a 300-amino-acid protein that has been characterized to contain multiple domains, including hydrophobic domain (HD), PAT-like … recycling ilfracombeWebView more Antibodies that detect HSD17B13 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry and ELISA. These antibodies target HSD17B13 in Human, Rat and Mouse samples. Our HSD17B13 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit … recycling ifrs

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Human hsd17b13

WebJan 7, 2024 · Recently, HSD17B13, a newly identified liver-enriched, hepatocyte-specific, lipid droplet-associated protein, has been reported to be strongly associated with the … WebBackground and aims: 17-Beta hydroxysteroid dehydrogenase 13 (HSD17B13) is genetically associated with human nonalcoholic fatty liver disease (NAFLD). Inactivating …

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WebApr 13, 2024 · Here are some possible explanations for the discrepancy between human and mouse loss-of-function mutations: (1) Different pathways: Loss-of-function (LoF) for the mouse and human HSD17B13 gene effect different fundamental pathways, as the two species are just different; (2) Different genes: The knockout mouse effects another gene … WebRecombinant Human HSD17B13 protein (Tagged) is a HEK 293 Full length protein 1 to 300 aa range, >=90% purity and validated in SDS-PAGE. Recombinant Human HSD17B13 …

WebAug 1, 2024 · The human HSD17B13 gene is located on chromosome 4 (4q22.1), and its expression is highly restricted to the liver, specifically in hepatocytes but not other cell types in the liver (2, 3). The... WebHsd17b13 Name hydroxysteroid (17-beta) dehydrogenase 13 Synonyms Pan1b Feature Type protein coding gene IDs MGI:2140804 NCBI Gene: 243168 Alliance gene page Transcription Start Sites 5 TSS Location & Maps more Sequence Map Chr5:104103308-104125254 bp, - strand From NCBI annotation of GRCm39 Genetic Map Chromosome 5, …

WebRecombinant Human HSD17B13 protein (Tagged) is a HEK 293 Full length protein 1 to 300 aa range, >=90% purity and validated in SDS-PAGE. WebJan 7, 2024 · The HSD17B13 gene was firstly cloned from the human liver cDNA library in 2007 and initially named SCDR9 (short-chain dehydrogenase/Reductase 9) (Liu et al., …

WebMar 30, 2024 · Recombinant human HSD17B13 protein was purified from Escherichia coli transformed with plasmid DNA harboring HSD17B13 transcript A or transcript D. Enzymatic activity was determined through...

Web17-b hydroxysteroid dehydrogenase 13 (HSD17B13) belongs to a 15-member family that is involved in various metabolic processes, including steroid hormones, fatty ac-ids, cholesterol, and bile acids (1). The human HSD17B13 gene is located on chromosome 4 (4q22.1), and its expres-sion is highly restricted to the liver, specifically in hepato- klean kanteen insulated canadaWebOnly some individuals with obesity develop liver fibrosis due to non-alcoholic fatty liver disease (NAFLD-fibrosis). We determined whether detailed assessment of lifestyle factors in addition to physical, biochemical and genetic factors helps in identification of these patients. A total of 100 patients with obesity (mean BMI 40.0 ± 0.6 kg/m2) referred for bariatric … recycling ideas for schoolsWebJun 1, 2024 · HSD17B13 is a newly identified liver restricted LD-associated protein. • HSD17B13 expression is markedly upregulated in the livers of patients and mice with … klean kut barber shop in hillsborough ncWebMar 29, 2024 · HSD17B13 rs72613567 protects against liver diseases and histological progression of nonalcoholic fatty liver disease: a systematic review and meta-analysis. … HSD17B13 - hydroxysteroid 17-beta dehydrogenase 13. Predicted to enable … recycling ilkleyWebHSD17B13. 17β-Hydroxysteroid dehydrogenase type 13 also known as 17β-HSD type 13 is an enzyme that in humans is encoded by the HSD17B13 gene. [5] [6] 17β-HSD13 is … klean kanteen insulated classic 32ozWebApr 3, 2024 · Published human genetic data indicate that a loss of function mutation in HSD17B13 provides strong protection against alcoholic hepatitis, cirrhosis, and NASH, with approximately 30-50% risk ... klean kanteen reflect dishwasherWebHsd17b13 ELISA Kit allows for the in vitro quantitative determination of Hsd17b13 concentrations in serum, plasma, tissue homogenates and other biological fluids. Size … klean max mophead